Allantoin

INCI: Allantoin · Comfrey-derived / synthetic

0.25–1%Studied Concentration Range¹
DailyUse Frequency
BarrierPrimary Function

Mechanism of Action

Allantoin increases water content in the skin's extracellular matrix and stimulates keratinocyte and fibroblast proliferation, supporting faster surface repair and a calmer, less reactive barrier.¹²

Clinical Evidence

Key finding: Allantoin-enriched wound-healing scaffolds tested at 0.25–1% concentrations showed measurably faster tissue repair and increased fibroblast activity versus scaffolds without it.¹²

Formulation Rationale

Active-ingredient formulas need a built-in buffer against sensitivity, particularly for first-time users. Allantoin's role is precisely that — letting Niacinamide and Alpha Arbutin do their work while keeping day-to-day wear calm.

Usage Protocol

Included at an effective supporting concentration in the Face Serum; applied with your normal AM/PM routine.

Safety Profile

Considered one of the safest, most broadly compatible soothing agents in cosmetic formulation, with essentially no known irritation risk.

Where You'll Find It

Niacinamide 10% Face Serum (₹649)

Bottom line: The reason this serum can be used daily by people new to active-ingredient skincare, without the usual adjustment period.

References

  1. Characterization and In Vivo Assay of Allantoin-Enriched Pectin Hydrogel for Skin Wounds
  2. Natural Film Based on Pectin and Allantoin for Wound Healing